We have won a case for a Ph.D. in Immunology for EB1, Outstanding Researcher following an elaborate Request for Evidence. The applicant had extensive research experience in the following areas: Pathology, Biochemistry, Molecular Biology and Immunology. USCIS requested additional documentary evidence to support the initial evidence that the applicant qualified based on his acting as judge of others’ work, numerous publications with accompanying citations as well as substantial evidence of “original” scientific contributions. We offered additional supporting documents that included letters from prominent military officials noting requests for applicant to review proposals, elaborate details on the significance and impact of the journals where the applicant’s research work had been published as well as documentary evidence to support the international reputation the applicant had gained as reflected by the multitude of citations in prominent scientific journals in his field. We provided evidence to confirm that the applicant’s ongoing noteworthy research was based on his “original” scientific contributions and that his work had a significant impact on the overall health and well-being of not only the U.S. military personnel but also the citizens of the country.